Diphenhydramine Hydrochloride and Zinc Acetate
Diphenhydramine Hydrochloride and Zinc Acetate is a topical combination medicine. Diphenhydramine hydrochloride is an antihistamine that temporarily relieves itching and pain by blocking histamines in the skin. Zinc acetate is a skin protectant that acts as an astringent to dry up oozing and weeping skin lesions caused by poison ivy, oak, or sumac.
Dosage by Body Weight
For external use only. For adults and children 2 years of age and older: Apply to the affected area not more than 3 to 4 times daily. For children under 2 years of age: Consult a doctor. Do not use on large areas of the body, on chickenpox, on measles, or with any other product containing diphenhydramine (including oral formulations).
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Topical diphenhydramine is generally contraindicated in newborns and infants due to increased risk of systemic absorption and toxicity. Consult a pediatrician.
- Body Weight
- 5-7 kg
- Dose
- Consult doctor
- Frequency
- As directed by physician
- Tracking Notes
- Typically corresponds to infants under 2 years. Safety and efficacy have not been established for this age group without professional medical advice.
- Body Weight
- 8-10 kg
- Dose
- Thin layer on localized area
- Frequency
- 3 to 4 times daily
- Tracking Notes
- Only use if the child is 2 years of age or older. Avoid applying to open wounds, blistered skin, or wide areas of the body.
- Body Weight
- 11-15 kg
- Dose
- Thin layer on localized area
- Frequency
- 3 to 4 times daily
- Tracking Notes
- Ensure child is 2 years of age or older. Do not use concurrently with oral diphenhydramine (Benadryl) to avoid toxic systemic levels.
- Body Weight
- 16-20 kg
- Dose
- Thin layer on localized area
- Frequency
- 3 to 4 times daily
- Tracking Notes
- Apply sparingly. Wash hands thoroughly after application to prevent accidental contact with the eyes or mouth.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Do not use | Topical diphenhydramine is generally contraindicated in newborns and infants due to increased risk of systemic absorption and toxicity. Consult a pediatrician. |
| 5-7 kg | Consult doctor | As directed by physician | Typically corresponds to infants under 2 years. Safety and efficacy have not been established for this age group without professional medical advice. |
| 8-10 kg | Thin layer on localized area | 3 to 4 times daily | Only use if the child is 2 years of age or older. Avoid applying to open wounds, blistered skin, or wide areas of the body. |
| 11-15 kg | Thin layer on localized area | 3 to 4 times daily | Ensure child is 2 years of age or older. Do not use concurrently with oral diphenhydramine (Benadryl) to avoid toxic systemic levels. |
| 16-20 kg | Thin layer on localized area | 3 to 4 times daily | Apply sparingly. Wash hands thoroughly after application to prevent accidental contact with the eyes or mouth. |
Formulation
Purpose
Temporarily relieves pain and itching associated with insect bites, minor burns, sunburn, minor skin irritations, minor cuts, scrapes, and rashes due to poison ivy, poison oak, and poison sumac. It also helps dry the oozing and weeping of poison ivy, oak, and sumac.
Generic Name
Diphenhydramine Hydrochloride and Zinc AcetateBranded Drug Names
Diphenhydramine Hydrochloride and Zinc Acetate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.